Epidemiology of epithelial ovarian cancer

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Molecular genetics and epidemiology of epithelial ovarian cancer (Review).

This review summarizes data from recent molecular genetic and epidemiology studies of the generic term 'female pelvic cancer'. The English-language literature was reviewed for genetic, epigenetic, epidemiologic and environmental risk factors. There are well-documented disparities among racial and ethnic groups with respect to epithelial ovarian ca...

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Epithelial ovarian cancer is the fifth commonest cancer among women and the leading cause of gynecological cancer death in the UK. Most women present with advanced disease, mainly because the nonspecific nature of the symptoms lead to diagnostic delays. Recent data have shown a fall in ovarian cancer mortality rates in the UK, but rates are still higher when compared to other European countries...

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A workshop on the epidemiology of ovarian cancer was held at the National Institutes of Health, Bethesda, Maryland, on September 30, 1 991 . The goals of the workshop were to address: (a) reproductive factors; (b) exogenous hormone use; (c) diet, life style, and health practices; (d) tumors of low malignant potential and nonepithelial germ cell ovarian tumors; (e) prospective studies; (I) deter...

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Epidemiology of Ovarian Cancer

Primary carcinoma of the ovary is the fourth most common cancer among women in developed countries. In 1999, almost 7,000 new cases were reported in theUnited Kingdom, which equates to a lifetime risk for women of 2%. Ovarian cancer is also the most common cause of death from a gynaecological malignancy there are about 4,500 deaths from the disease in the UK every year [1]. Worldwide, ovarian c...

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epigenetic brca2 gene in epithelial ovarian cancer

background ovarian cancer is the most common fatal gynecologic malignancy in women. the brca2 gene has a role in regulation of cell cycle during proliferation, differentiation and dna repair. changes in the methylation of brca2 may be an effective mechanism for ovarian cancer. objectives the aim of the present study was to evaluate the association between ovarian cancer and methylation status o...

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ژورنال

عنوان ژورنال: Best Practice & Research Clinical Obstetrics & Gynaecology

سال: 2017

ISSN: 1521-6934

DOI: 10.1016/j.bpobgyn.2016.08.006